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The reduced Trx transfers electrons to oxidatively damaged proteins or ROS directly

In the condition known as functional hypothyroidism, the thyroid hormones cannot control metabolism efficiently because of the excessive synthesis of rT3 and the lack of T3

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Indeed, tirzepatide may represent a step forward towards nephroprotection mediated by drugs acting on the incretin system [88]

Oncogene (2004) 23(48):791827.10.1038/sj.onc.1208081 105 EngenJRWalesTEHochreinJMMeynMAIIIBanu OzkanSBaharIet alStructure and dynamic regulation of Src-family kinases