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Conversely, H3K4me2, an activating mark associated with gene expression, decreases by 65%, reducing expression of genes essential for sperm development (92)

Theyre also among the most vulnerable structures to free radical damage

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It is advisable to avoid valproic acid, as it can impair liver mitochondrial function and cause hepatotoxic, while carbamazepine and phenytoin can decrease vitamin B12 and folic acid levels, therefore, these drugs should be avoided whenever possible

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