If you have unused HSA or FSA funds, semaglutide-based weight management programs may be a practical way to invest those dollars in your long-term health while staying within IRS guidelines.
Downsides include occasional headaches during dose increases and a little more constipation than I had on tirzepatide
Dual versus triple agonist mechanism Tirzepatide is built on a GIP backbone
This aligns well with the first dose experience that many GLP-1 users describe, where that initial adjustment period benefits from scheduling flexibility
doi:10.1093/ajcn/69.6.1135 Birkeland E, Gharagozlian S, Gulseth HL, Birkeland KI, Hartmann B, Holst JJ, et al
This format allows for predictable absorption and long-acting appetite regulation, making it suitable for patients requiring stable, sustained GLP-1 exposure