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#drugdiscovery #pharma #obesity Great overview of the oral SM GLP-1 landscape worth mentioning though is Structure Therapeutics ($GPCR) and their aleniglipron (GSBR-1290), which is probably the closest structural cousin to orforglipron currently in the clinic

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Addictive Behavior It is believed that GLP1 receptor agonists may positively influence addictive behavior, such as drug and alcohol use, eating, and smoking, through impacting the reward center in the brain