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A peptide isolated from phage display libraries is a structural and functional mimic of an RGD-binding site on integrins

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PINCH-ILK-Akt Survival Signalling TB-500 has been shown to form a functional complex with PINCH and integrin-linked kinase (ILK), resulting in activation of the survival kinase Akt/PKB which is necessary for thymosin beta-4s effects on cardiomyocyte survival, migration, and cardiac function

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