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The mechanism of action of semaglutide involves binding to GLP-1 receptors, which are present in the brain, particularly in areas regulating appetite and satiety

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Participants on the highest dose lost an average of 22.5% of their body weight over 72 weeks

How Tirzepatide Works Tirzepatide is a unique medication that mimics the effects of two naturally occurring incretin hormones in the body: glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)