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These include nausea, vomiting, diarrhoea, constipation, abdominal discomfort, and reduced appetite, as documented in the UK SmPC

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Based on the above results and our previous findings that inhibiting the cGAS-STING signaling pathway could suppress ferroptosis in skeletal stem cells derived from costal cartilage tissue [34], we hypothesized that GLP-1RAs might inhibit ferroptosis of chondrocytes by suppressing the activation of the cGAS-STING signaling pathway, and promote the synthesis of glycosaminoglycans and chondroitin sulfate, thereby alleviating the development of RA

To view a copy of this license, visit About this article Cite this article Ribeiro-Parenti, L., Jarry, AC., Cavin, JB