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J Biol Chem 278(20):1768017687 Logue SE, McGrath EP, Cleary P, Greene S, Mnich K, Almanza A et al (2018) Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy

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The authors suggested that the lack of VIP-mediated gland secretion might promote a hyper-inflammatory airway environment that contributes to CF lung disease