#MASH #Hepatology #GLP1 #PharmaInsights To view or add a comment, sign in #MoleculeMonday: Thalidomide was once a global tragedy
Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, exemplifies our dedication to cutting-edge care for managing type 2 diabetes and weight
Dosing in the Phase 3 Diabetes Trial (TRANSCEND-T2D-1) A1C reduction: -1.7% to -2.0% across doses (from baseline 7-9.5%) Weight loss at 12 mg: 16.8% (-36.6 lbs) at 40 weeks Discontinuation due to adverse events was relatively low across all doses, similar to the patterns seen in TRIUMPH-4 The diabetes population typically loses less weight on GLP-1 drugs than the obesity-only population, which is consistent with what was observed: ~17% weight loss in T2D vs
Despite widespread demand, affordability and insurance coverage lag far behind medical efficacy
Eat A Balanced Diet A balanced, whole-foods based, anti-inflammatory diet is what I would recommend to anyone , and certainly to anyone who is looking for help with weight loss
The result of this effort was semaglutide