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This medication was shown to reduce the risk of CKD progression and renal failure, as well as dialysis initiation, in the Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease trial, which involved participants with type 2 diabetes who had albuminuria and advanced CKD

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In large-scale cardiovascular outcome trials, enhanced GLP-1 signaling has reduced the risk of atherosclerotic ischemic events, potentially because GLP-1 retards the growth and increases the stability of atherosclerotic plaques

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