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For survival analysis, AKP tumour-bearing mice were generated as above, and 26 days after induction, they were treated with 150 mg kg 1 5FU (i.p.) 250 mg kg 1 metformin (o.g.) three times weekly

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Many patients on comprehensive longevity protocols including SS-31 report gradual body composition improvements, though these are difficult to attribute specifically to SS-31 vs the full protocol context