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The STEP 1 clinical trial is even more sobering: participants who lost 17.3% of their body weight with semaglutide regained 11.6 percentage points of that loss within one year of withdrawal, leaving a net loss of only 5.6% from their original weight
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The pharmacokinetics suggest a half-life comparable to tirzepatide
The hormone is called glucagon-like peptide-1 (GLP-1)
Transforming Lives, One Step at a Time Keep reading What to Eat While on a GLP-1 When a GLP-1 medication like semaglutide or tirzepatide curbs your appetite, the challenge shifts from eating less to eating well
doi.org/10.1097/MCO.0000000000000162 7 Wilding JPH, et al
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