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Two hundred and one adolescents with clinical obesity between 12 and 18 were entered in a trial to test the effect of the weight-loss drug semaglutide, marketed under the name Ozempic when it is prescribed for diabetes and Wegovy when prescribed for weight loss

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Initial weight loss: 2% within 4 weeks Maximum weight loss: 15% by week 68 with lifestyle changes Insurance coverage for Wegovy is based on provider policies and coverage criteria, regardless of prescriber specialty

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Comparison: Studies comparing GLP-1RA therapy to placebo, no GLP-1RA, or other active comparators (e.g., DPP-4 inhibitors)

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