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Segn las investigaciones, tiene una accin protectora sobre las neuronas, el declive cognitivo y el deterioro de la memoria relacionados con el envejecimiento o las enfermedades degenerativas, este efecto se explica por un efecto antioxidante sobre las neuronas y la circulacin sangunea

107,108 Beyond direct effects on insulin signaling, SIRT1 indirectly modulates insulin sensitivity by regulating autophagy via the mTOR pathway

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Following these initial results, the SOUL trial was commenced to specifically study the efficacy of oral semaglutide on cardiovascular health and find if oral semaglutide can be more beneficial than placebo