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The uptake of mitochondrial iron can be mediated by the MCU, which plays a critical role in mitochondrial calcium absorption [108]

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investigated the overproduction of SOD-2 (Mn-SOD), which depletes hippocampus superoxide and protects against memory loss in AD mice models [89, 90]

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The labeling warns about acute kidney injury due to volume depletion and instructs monitoring of renal function in patients reporting adverse reactions that could lead to it