269 XiaoA.ZhangY.RenY.ChenR.LiT.YouC.et al (2021)
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With powerful antioxidant and anti-inflammatory properties, GHK-Cu helps rejuvenate damaged skin, soften fine lines, and restore a healthy glow
Morning: Gentle cleanser Vitamin C serum (allow full absorption) Hyaluronic acid serum Niacinamide (optional, can be in moisturizer) Moisturizer Sunscreen SPF 30+ Evening: Oil cleanser (if wearing sunscreen/makeup) Gentle water-based cleanser Copper peptide serum Additional peptide serum (optional, like Matrixyl ) Heavier moisturizer or night cream This routine separates vitamin C (morning) from copper peptides (evening) while delivering multiple anti-aging mechanisms
PRP treatment for dark circles , often known as Platelet-Rich Plasma Therapy, uses the growth factors in your own blood to replenish the skin behind your eyes
For macrophage polarization experiments, cells were then treated with either human recombinant IL-4 (10 ng/mL, Cedarlane Labs, Burlington, ON) or IFN- (10 ng/mL, eBioscience, San Diego, CA) for 48 h