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Considerations: Proper spray technique (appropriate angle, avoiding the septum) Alternating nostrils per dose Using a saline rinse periodically to support nasal mucosal health Discontinuation and route change if persistent irritation develops Patients with allergic rhinitis, chronic sinusitis, or significant septal deviation may be poor candidates for nasal delivery and should be considered for injection or oral spray instead
Eat small amounts of food at more frequent intervals rather than 3 meals a day
Similarly, post hoc analyses of Harmony Outcomes and DECLARETIMI 58 suggested preserved benefit with concomitant therapy, but these studies were not powered to establish additive efficacy of the combination [26, 27]
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