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That brown fat was not found by 18 F-fluorodeoxyglucose ( 18 F-FDG) uptake using PET/CT in areas of MSL tissue (281) does not rule out the brown fat hypothesis as there may be browning of MSL fat rather than as strict replication of brown adipocytes

CPP-CAND disrupts FOXO4-p53 foci and induces apoptosis through caspase-dependent pathways FOXO4 is progressively recruited to euchromatin foci following senescence induction and is retained in the nucleus of senescent cells through its interaction with p53, contributing to the maintenance of the senescent state 34

doi:10.1056/nejmoa2203364 106 Ng JWG, Cairns SA, OBoyle CP

Cancer metabolism: the role of ROS in DNA damage and induction of apoptosis in cancer cells

Metabolic effects of the combination of furosemide and captopril in rat