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Freezing causes irreversible changes to the protein structure of GLP-1 molecules, rendering the medication ineffective

The overall rating for risk of bias obtained through the RoB2 tool was included as part of the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach [11]

Blood glucose was measured directly after collection using a handheld glucometer (Accu-Chek Compact Plus

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Here in 2026, weve seen these medications fundamentally change the conversation around weight management, offering a level of efficacy that was once unimaginable

The acetaminophen infusion is continued by repeating the last IV infusion dose in the protocol (e.g., 100 mg/kg infused over 16 hours on repeat)