, 2016, Turgut and Tandogan, 2011)
Controversies and Critical Perspectives Despite promising findings, the ASD-CFDS connection remains for further discussion and analysis: Causation vs
As shown in Table 1, most of the available data derive from preclinical in vivo models, with marked heterogeneity in extract preparation, doses tested, and outcome measures
ROS induce inflammation by increasing the production of pro-inflammatory cytokines, especially IL-1, IL-8, and TNF- (176, 177)
L.PitoutI
Although the reaction mixture was prepared under anaerobic conditions, catalase was added to ensure that if reduced SmTGR were to react with any available dioxygen, the resulting H 2 O 2 would quickly be disproportionated and moreover, this activity further depletes oxygen with the sample