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Increases in the levels of intracellular aspartate via SLC1A3 contribute to nucleotide synthesis and maintain the electron transport chain and TCA cycle 114

[38] Unlike previously established device category codes where CMS has made an anatomical specification based on a clear anatomical distinction in the device indication, such as a ureter and the bronchi, a different indication such as drug-delivery rather than angioplasty, or different mechanisms of action like radiofrequency versus ultrasound, with regard to the nominated technology, we did not believe at the time the code was established, nor do we believe at this time, that such an anatomical distinction is necessary for C1831

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However, when a pre-existing medical condition like heart disease or gallbladder issues is present, the evaluation becomes more complex