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Acknowledgments This project was initiated by the Obesity Management Collaboration-UK (OMC-UK), which is a professional support network of healthcare professionals with an interest in obesity treatment

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TITR will likely be more clinically beneficial than TIR as fluctuations outside of TITR may be better predictors of complications and offer a better therapeutic window for intervention

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Mechanical factors during injection can exacerbate local irritation

Semaglutide is a GLP-1 receptor agonist that slows gastric emptying but does not affect hormonal contraceptive mechanisms No pharmacological interaction between Ozempic and levonorgestrel has been documented in clinical studies or MHRA guidance Vomiting within three hours of taking emergency contraception requires immediate contact with a healthcare professional for possible replacement dose The copper IUD remains the most effective emergency contraception option and is unaffected by Ozempic or gastrointestinal symptoms Common Ozempic side effects include nausea, vomiting, and diarrhoea, which may compromise absorption of any oral medication Table of Contents Does Ozempic Affect Levonorgestrel Emergency Contraception