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elegantly demonstrated that islets incubated in media containing human islet supernatants exhibit increased insulin secretion in a GLP-1R-dependent manner (58)

Conversely, older adults with certain gastrointestinal conditions, pancreatic history, or severe kidney impairment may not be suitable candidates regardless of age

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17 However, scintigraphy typically does not capture small intestinal transit times, limiting its utility in evaluating the effects of altered motility on drug absorption

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