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The tirzepatide B12 combination is common but not universally tolerated

20 These results were consistent in patients regardless of the etiology of their vitamin B 12 deficiency, including malabsorption states and pernicious anemia

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4 In asymptomatic patients with low-normal levels of vitamin B 12 (200 to 350 pg per mL [147.56 to 258.23 pmol per L]), elevated levels of the precursor compounds homocysteine and methylmalonic acid may prompt a decision to supplement patients with vitamin B 12

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