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This downstream regulatory profile resembles the transcriptional shift induced by KL1 (Extended Data Fig

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In Grx1-roGFP2, the genetic fusion of a glutaredoxin to roGFP2 increases the effective local glutaredoxin concentration by 1000-fold [42], thereby allowing roGFP2 to equilibrate more rapidly with changes in E GSH

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By addressing the multifaceted nature of ACL injuries, these approaches aim to reduce injury incidence, optimize recovery, and enhance overall athletic performance