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Ammonia readily crosses the blood-brain barrier and is thought to inhibit glutamate uptake, thereby increasing extracellular glutamate concentrations in the brain and resulting in activation of NMDA receptors

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Stock solutions A stock solutions of 0.1 mol/L N-Hcy-Lys and 0.05 mol/L Cys, Hcy, GSH were prepared in 1 mol/L and 0.1 mol/L HCl, respectively