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Such a finding suggests additional undiscovered mechanisms in older fathers that may influence the incidence of autosomal dominant disorders in offspring

Shatsky[23], who examined evidence derived from the use of oral and intramuscular administration, indicated that high dose oral administration appeared to be safe, effective and cost-effective, although long term clinical trials were required to confirm this

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For the PD model, rats with unilateral 6-hydroxydopamine (6-OHDA) lesions in the substantia nigra were used to replicate PD pathology

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