consider ECG if clinically indicated Nutritional status : Assess current dietary intake, eating patterns, and screen for disordered eating behaviours Mental health evaluation : Screen for depression, anxiety, or other psychiatric comorbidities that may affect treatment adherence or outcomes Weight and metabolic parameters : Record baseline weight, BMI, waist circumference, and relevant blood tests (HbA1c, lipid profile, renal function) Pregnancy status : Exclude pregnancy and discuss contraception requirements (Wegovy is contraindicated in pregnancy) Treatment should begin with a dose of 0.25 mg once weekly, increasing every 4 weeks (0.5 mg, 1.0 mg, 1.7 mg) to reach the maintenance dose of 2.4 mg if tolerated
Your healthcare provider will monitor your progress and adjust dosages as needed
Starting a medication like Ozempic or Wegovy can seem simple on paper
For example, the intervention of KEAP1 inhibitors, such as natural coumarins, promotes Nrf2 activation, which reduces oxidative stress and inflammation in IBD by inhibiting NF-B and enhancing antioxidant responses, as documented (261)
Use supplements strategically: Incorporate protein bars and liquid protein when whole-food intake is insufficient
Consult your doctor before starting on any medication to avoid complications like overdosing if you are already taking any supplements