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In spite of a wider array of available options in drug selection today, the incidence of refractory epilepsy remains still high, corresponding to 30% of all epilepsy patients

Collectively, these findings underscore the unique capacity of natural products to modulate tumorimmune crosstalk at multiple levels, ranging from immune priming and checkpoint regulation to metabolic and microbial reprogramming

Cell 166 , 15121525 (2016)

Second, lower levels of MTHF production mean that the methionine cycle slows down, which can lead to the accumulation of homocysteine

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Vitamin D toxicity can also cause gastrointestinal distress, and it can lead to a buildup of calcium that can lead to bone and kidney pain