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20 Sitagliptin is the only DPP-4 inhibitor to show significant reduction of BP

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Renal function must be considered, as some GLP-1 agents require dose adjustment or have limitations in advanced chronic kidney disease

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Biochemical Pharmacology, 51(5), 443-451

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B12 absorption requires intrinsic factor, a glycoprotein produced by parietal cells in the stomach lining

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