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It is composed of three amino acids: cysteine, glycine, and glutamic acid
(5)KO+5-HTP group: TPH1 knockout mice were treated i.p with APAP and 5- Hydroxytryptophan (5-HTP, precursor of 5-HT which can reload the 5-HT content, at a dose of 75 mg/kg/day for 3 days by subcutaneous injection before APAP administration) as previously reported 19
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Dysfunction of GSK-3 is involved in the pathogenesis of several diseases, including neuropsychiatric disorders 71
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