After 56 weeks: Placebo group lost 1.6% of body weight Starting dose (3.75/23 mg) group lost 5.1% of body weight Top dose (15/92 mg) group lost 10.9% of body weight Beyond weight loss, the CONQUER trial showed significant improvements in blood pressure, waist circumference, lipid profiles, glycemic parameters, and inflammatory biomarkers compared to placebo
Pendulum requires months of consistent use before meaningful effects are typically reported
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As body weight decreases, the bodys energy balance recalibrates
This matters because muscle supports strength, balance, glucose handling, metabolism, mobility, and long-term weight maintenance
Saxenda: The Daily Option with an Established Track Record Saxenda was one of the first GLP-1 medications approved specifically for weight management