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GLP-1 projections from NTS to NAc and VTA promote satiation and reduce food reward, while orexinergic projection from lateral hypothalamus to NTS suppresses satiation and increases food reward ( The paraventricular thalamic nucleus (PVT) neurons receive GLP-1 innervation from NTS and express GLP-1R (Ong et al., 2017)
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Meta-analyses of the CKD subgroups in the atherosclerotic CV disease and HF trials of SGLT2 inhibitors similarly demonstrated benefits on CV, HF, and renal outcomes
L.ParthsarathyV.FaivreE.HolscherC
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