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The SURMOUNT-5 trial later confirmed that tirzepatide produced 47% greater weight loss than semaglutide in a head-to-head comparison, solidifying its position as a leading option for weight management
Current evidence from manufacturers and clinical guidelines suggests caution, though research specifically measuring medication transfer into breast milk remains sparse for most GLP-1 compounds
Obal F Jr, Krueger JM
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A "natural" origin of a substance tells you nothing about overall safety at a synthetic dose, by an unphysiological route, in a manufactured form whose purity is not independently verified
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