If fasting glucose rises above 110 mg/dL while on combination therapy, the protocol needs adjustment
Table 3 Results of a 52-week Monotherapy Trial in Adults with Type 2 Diabetes Mellitus a Figure 3 Mean HbA 1c for Adult Patients with Type 2 Diabetes Mellitus who Completed the 52-week Trial and for the Last Observation Carried Forward (LOCF, intent-to-treat) data at Week 52 (Monotherapy) Combination Therapy Add-on to Metformin In this 26-week trial, 1,091 adult patients with type 2 diabetes mellitus were randomized to liraglutide injection 0.6 mg, liraglutide injection 1.2 mg, liraglutide injection 1.8 mg, placebo, or glimepiride 4 mg (one-half of the maximal approved dose in the United States), all as add-on to metformin
They may recommend changing your injection site, lowering your dose, or using a soothing cream to help with irritation
A note about stimulant medication and addiction: Stimulants are a Schedule II medication, and some people abuse ADHD medication
The Wegovy prescribing information carries a warning about pancreatitis based on post-marketing reports, and the STEP trials excluded patients with a pancreatitis history [4]
These medications target specific hormones, such as GLP (glucagon-like peptide) and GIP (glucose-dependent insulinotropic peptide), which influence insulin secretion, glucagon production, and feelings of fullness
