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Adults with Down syndrome are at high risk for developing Alzheimers disease because of their unique biology, usually starting in their late 40s, and the vast majority of individuals with Down syndrome will eventually develop the disease by their late 60s, said principal investigator Benjamin Handen, PhD, professor of psychiatry at Pitt

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So even if you dont have a gross deficiency of B12 throughout your life, you may feel the biochemical effects of subclinical B12 deficiency in energy production and how you feel