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Introduction Glioma is a threatening primary malignancy tumor in the central nervous system ( Recently, immunotherapy represented by PD-1/PD-L1 and CTLA-4 has shown excellent clinical effects on numerous tumors such as melanoma and non-small cell lung cancer ( The glioma immune microenvironment is composed of glioma cells, immune cells, cytokines and so on ( Ferroptosis is a form of regulated cell death driven by lipid peroxidation, a consequence of imbalance between cell metabolism and redox homeostasis ( Overview of Ferroptosis and Potential Singling Pathway in Glioma The main characteristics of ferroptosis include: cell morphology (mitochondria crista, volume reduction, and increase of membrane density)

creatinine) when taking blood, in order to correctly interpret the results

The Chronicle uncovered at least 42 adverse events associated with Empowers drugs, but that list is not comprehensive

In addition, PS can participate in the coagulation process, regulating platelet aggregation and vasoconstriction (Naozuka et al., 2024)