In particular, the first study demonstrated that, along with improvements in anthropometric parameters, HOMA-IR reduced in both treatment arms, but liraglutide 1.2 mg/day was superior to metformin also in reducing glucose levels at 120 min during OGTT [57]
Liou AP, Paziuk M, Luevano JM Jr., Machineni S, Turnbaugh PJ, Kaplan LM
Tirzepatide spans 2.5mg to 15mg
Eli Lilly and Company's retatrutide 12 mg hit 28.3% mean weight loss at 80 weeks in the pivotal Phase 3 obesity trial TRIUMPH-1
Although the incidence of adverse events (AEs) between bimagrumab and placebo was similar, there was a transient increase in pancreatic and liver enzyme levels observed with the use of bimagrumab [97]
Aziz AA, Kenney LS, Goulet B, Abdel-Aal E