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Meaningful change was defined as 0.2 logMAR [18]

DCA, deoxycholic acid

Phase II data showed weight loss of up to approximately 20% at 52 weeks, with monthly dosing that could offer meaningful convenience advantages over weekly injections

The results, which were published in the Lancet on Thursday, are very encouraging for the safety and efficacy of orforglipron in people with type 2 diabetes, says Daniel Drucker, an endocrinologist at the University of Toronto, adding that he is awaiting further clinical trial results of the drug in people with obesity

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