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The quinone methide intermediate of berbamine in vitro and in vivo metabolism were detected by LC-MS/MS, which can be covalently bind with NAC to generate NAC-derived adducts

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Understanding how the AOD-9604 peptide works reveals a distinct metabolic approach that targets fat tissue directly without modifying hunger signals, cortisol levels, or appetite hormones

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doi: 10.3402/fnr.v59.25702