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doi: 10.1016/j.psyneuen.2022.105894 72 HenneghanAMLewisKAGillEKeslerSR

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The clearest examples: Acetaminophen absorption is delayed but total bioavailability is unchanged Furosemide peak levels are about 30% lower, though total exposure is similar Atorvastatin and rosuvastatin show no clinically meaningful change Digoxin showed no significant interaction in studies Warfarin shows slight changes in INR that warrant closer monitoring For most oral medications taken at the same time each day, the body adapts to the new absorption profile within a few weeks

Most gastrointestinal side effects are mild to moderate in severity and resolve without discontinuing treatment