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161 In summary, dual and triple agonists related to GLP-1 represent significant advances in the field of diabetes treatment, 167,168 demonstrating the future trend of enhancing therapeutic effects by targeting multiple biomarkers

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Semaglutide trials have enrolled tens of thousands of participants

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Clinical trials have demonstrated average weight reductions of approximately 15% over 68 weeks

Summary: Allergic reactions to GLP-1 agonists are uncommon, affecting fewer than 1 in 100 people, and range from mild injection site reactions to rare anaphylaxis requiring emergency treatment