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KPV acts directly on MC1R/MC4R receptors on macrophages and epithelial cells, reducing IL-6 and TNF- at the transcription level [7,8]

Recent studies conducted within our group [83] have focused on clarifying the coordinated effects of fasting, re-feeding and exendin-4 administration on the activity of AMPK and S6K in the VMH and LH

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A similar trend of a protective effect of GLP-1 use on dry AMD development was seen when compared to insulin and metformin by one year and compared to SGLT-2i by three years of drug duration