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10, 11, 12, 14, 15, 16, 17 This animal model provides an understanding of how exogenous agents, such as PPA, can cause reversible behavioral, metabolic, neuropathological and neurophysiological changes associated with ASD

Potency and PK anchors: Lau 2015 (cAMP EC50 6.2 pmol/L), Boianelli 2024 (free fraction 0.36%), FDA 2021 (weight-change EC50 54.6 nmol/L)

The ability of L-theanine to generate relaxing alpha brain waves is equally well-documented

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