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Recovery timelines vary by condition, but many patients notice improvements within a few weeks

Studies show that oligomenorrhoeic PMOS patients have elevated kisspeptin pulse frequency but a broken temporal coupling between kisspeptin and LH pulses meaning kisspeptin is firing, but it is not translating into coordinated ovulatory signalling

These times align with natural GH pulse patterns and maximize the secretagogue effects

The fat cell targeting mechanism remains active, but with less total adipose tissue available to mobilize, changes occur more gradually

This does not change the total amount of medication (10 mg), but it does change how much liquid you have to draw up for a specific dose

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