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Because individual responses vary, careful monitoring by a healthcare professional is important

Less commonly (21%), amyloid deposition is localized, meaning precursor protein synthesis, amyloid fibril deposition, and clinical manifestations are confined to the GI tract [8, 9]

Employers have largely attempted to avoid these cost increases, with a 2023 Accolade survey finding that approximately 60% of employers do not intend to cover GLP-1s in 2024