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PCOS is often linked to insulin resistance, affecting about 70% of individuals with the condition, and increases the risk of type 2 diabetes, cardiovascular disease, endometrial cancer, and metabolic syndrome

The move builds on its recent billion-dollar acquisition of the obesity-focused biopharma company Metsera

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Clinical trials show tirzepatide produces numerically greater weight loss than semaglutide at matched doses in some cohorts, though individual responses vary significantly

Pain related to active inflammation inside the abdomen is less common but typically more severe and persistent