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In over 1,000 vitamin B12 shots, Ive never seen anyone have any issues with either, but there is a theoretical risk factor for both

2018 Oct 01;112(10):423-435

Ann Endocrinol (Paris)

Recreational Nitrous Oxide Causing Deep Vein Thrombosis and Subacute Combined Degeneration: Whip It Real Good

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The honest, educational picture is more nuanced