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Stay in communication with your provider about how you're feeling at each step

For people whose sleep apnea is severe enough to affect daily functioning, the greater weight loss from tirzepatide or potentially retatrutide could be a deciding factor in medication choice

The process is identical for both compounds

Price and access will shape real-world impact

Improving the Theranostic Potential of Exendin 4 by Reducing the Renal Radioactivity through Brush Border Membrane Enzyme-Mediated Degradation

Patients who switched from tirzepatide to orforglipron maintained a mean 74.7% of their body weight reduction from the SURMOUNT-5 trial compared with those in the placebo group, which maintained a mean 49.2% of their weight loss