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That difference is absolute

GLP-1 agonists (semaglutide, tirzepatide) are often covered for diabetes and increasingly for obesity if you meet BMI criteria and have related comorbidities

For research use only basic overview, not definitive

In particular, elective procedures with high consequence complications, including TJA, warrant carefully designed observational cohorts with validated patient-reported outcomes, wound surveillance, and adverse event monitoring

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